The royal figure surrenders his honor as Duke of York.
Prince Andrew is surrendering his honors, such as the York's Duke, he has stated in a personal statement.
He has been under growing pressure over his associations with sex offender the financier, with demands for the Palace to take measures against him.
That now seems to have caused the figure deciding to of his own accord give up his honors and to surrender participation of the Order of the Garter.
In his statement he said he continued to "strongly dispute the accusations against me".
"In talks with the monarch, and my close and broader family, we have concluded the ongoing allegations about me take away from the work of the monarch and the royal household," said a announcement from Prince Andrew.
"I have chosen, as I always have, to put my obligation to my family and nation first.
"I support my resolution five years ago to stand back from public life.
"With His Majesty's approval, we believe I must now go a further step. I will therefore no longer employ my title or the honours which have been conferred upon me. As I have said previously, I vigorously dispute the claims against me."
The royal has encountered a series of issues, including a court case he settled with the plaintiff, questions about his finances and his involvement with an alleged foreign agent.
He will stay a prince - but will stop to be the Duke of York, a designation granted from his parent, the Queen Elizabeth II.
Andrew had already ceased to be a "working royal" and had forfeited the use of his HRH title and no longer participated at official royal events. His status now will be even more diminished.
His previous partner will be known as Sarah Ferguson and no longer Duchess of York, but their daughters will continue to have the designation of princesses.
Prince Andrew has been under intense scrutiny over his connections with convicted sex offender the financier, more lately including doubts about when he had really ended ties.
In his BBC Newsnight interview, he had said that he had cut off all ties with the financier after they had been seen together in the city in late 2010.
But emails sent in February 2011 later emerged suggesting that the prince had in private remained in contact with him, such as sending a note: "Keep in close touch and we'll play some more soon!"
There had been mounting displeasure in Buckingham Palace at the issues that persisted to surround the prince.
In the coming days a book released after death by Virginia Giuffre will be published which is likely to draw further attention on his connection with the plaintiff and Epstein.
